Peptide Database

Peptide NameDefensin alpha 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC428H706N126O136S9

DescriptionStandard

        MRTLALLTAILLVALQAQAGPLQARCDEAAGQEQPGVDDQDISISFACDKISALQVSGSTRGLACTCRLVYCRPAERRAGSCIVGGVGFAYCCSLAD
    

Molecular Weight10081.53 Da

Isoelectric Point (pI)5.21

Net Charge (pH 7.0)-1.56

Net Charge (pH 7.4) -1.91

Charge Density (pH 7.0) -0.0161

GRAVY Index0.34

Hydrophobic Moment 0.60

Boman Index0.11

Instability Index50.80

Aliphatic Index 97.73

Aromaticity 0.0412

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4190.19

LogP -49.57

H-bond Donors 154.0

H-bond Acceptors 144.0

Rotatable Bonds 332.0

Heavy Atoms 699.0

Ring Count 7.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314990 VERIFIED: NO

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyDefensin

Tax ID9483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence