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MYP_087297
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C18H31N5O7
Standard
Sequence
AAATP
Physicochemical Analysis
429.47 Da
5.57
-0.20
-0.39
-0.0408
0.62
0.10
0.39
8.00
60.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
191.16
-2.72
6.0
7.0
9.0
30.0
1.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025961 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
6470.0
IC50
PaperGallego M., Aristoy M.-C., Toldr¨¢ F.. Dipeptidyl peptidase IV inhibitory peptides generated in Spanish dry-cured ham. Meat Science 96, 757-761, 2014.
RECORD: Rec_0176292 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory
PaperMart¨ªnez-S¨¢nchez S. M., P¨¦rez-S¨¢nchez H., Gabald¨®n J. A., Abell¨¢n-Alem¨¢n J., Montoro-Garc¨ªa S.. Multifunctional peptides from Spanish dry-cured pork ham: endothelial responses and molecular modeling studies. Int. J. Mol. Sci., 20, 4204, 2019.
RECORD: Rec_0240892 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Angiotensin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
100 μM
IC50
RECORD: Rec_0249682 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
100.0
IC50
PaperEscudero E., Mora L., Fraser P.D., Aristoy M.-C., Arihara K., Toldra F.. Purification and identification of antihypertensive peptides in Spanish dry-cured ham. Journal of Proteomics, 78, 499-507, 2013.