Peptide Database

Peptide NameDenileukin diftitox

Function Ontology

Anticancer

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1237H1943N335O403S8

DescriptionStandard

        MGADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEINFETRGKRGQDAMYEYMAQACAGNRVRRSVGSSLSCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTA
    

Molecular Weight28212.18 Da

Isoelectric Point (pI)5.44

Net Charge (pH 7.0)-5.21

Net Charge (pH 7.4) -5.71

Charge Density (pH 7.0) -0.0204

GRAVY Index-0.66

Hydrophobic Moment 0.86

Boman Index-0.08

Instability Index40.03

Aliphatic Index 67.65

Aromaticity 0.0863

Extinction Coeff. Reduced 32890.00

Extinction Coeff. Oxidized 33015.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0242109 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyCytokine/protein therapeutic

Tax ID562

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer

Half-Life1.16-1.3 h