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MYP_087203
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Basic Information
PEP-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C136H195N35O33
Standard
Sequence
KETWWETWWTEWSQPKKKRKV
Physicochemical Analysis
2848.22 Da
9.82
2.76
2.55
0.1316
-2.04
0.38
-0.39
19.89
13.81
0.2381
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1143.39
-5.22
42.0
36.0
91.0
204.0
11.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0139533 VERIFIED: YES
Provenance & Taxonomy
Derived from [Virus]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID16945333 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16945333/
RECORD: Rec_0147637 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Cysteamide at C-Terminus (FITC labelling)
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0165438 VERIFIED: YES
Provenance & Taxonomy
Simian virus [Virus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium
64 μM
MIC
PMID16945333;28556271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16945333/
RECORD: Rec_0176319 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
C. trachomatis
PaperThe cell-penetrating peptide, Pep-1, has activity against intracellular chlamydial growth but not extracellular forms of Chlamydia trachomatis.
RECORD: Rec_0181847 VERIFIED: YES
Provenance & Taxonomy
Derived from [Virus]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis (KCTC 1917)
64 μM
MIC
PMID16945333 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16945333/
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