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MYP_087203
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Basic Information
PEP-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C136H195N35O33
Standard
Sequence
KETWWETWWTEWSQPKKKRKV
Physicochemical Analysis
2848.22 Da
9.82
2.76
2.55
0.1316
-2.04
0.38
-0.39
19.89
13.81
0.2381
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1143.39
-5.22
42.0
36.0
91.0
204.0
11.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011563 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
PEP
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID24416126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24416126/
RECORD: Rec_0027951 VERIFIED: NO
Provenance & Taxonomy
Synthetic construct [Synthetic]
Synthetic CPP
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide
9 L/LacZ cells
Cellular uptake assay
Evidence URLhttps://patents.google.com/patent/US20060035815 PatentUS20060035815
RECORD: Rec_0032576 VERIFIED: YES
Provenance & Taxonomy
Simian virus [Virus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
MDRPA 2
64 μM
MIC
PMID16945333;28556271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16945333/
RECORD: Rec_0049224 VERIFIED: YES
Provenance & Taxonomy
Simian virus [Virus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus 3
64 μM
MIC
PMID16945333;28556271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16945333/
RECORD: Rec_0058477 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Pep-1
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide
HS-68; NIH-3T3
Fluorescence-based uptake assay
PMID11731788 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11731788/
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