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MYP_087201
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Basic Information
K 11-Amurin-2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C113H183N23O21S2
Standard
Sequence
FLPLLLAGLPKFLCLVFKKC
Physicochemical Analysis
2263.93 Da
9.39
2.74
2.50
0.1369
1.53
0.53
0.47
30.88
156.00
0.1500
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
676.70
2.23
24.0
26.0
72.0
159.0
5.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031966 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
MRSA
16 μM
MIC
PMID29366784 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29366784/
RECORD: Rec_0032493 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Horse erythrocytes
50 %
Hemolysis
PaperPubMed PMID: 29366784 PMID29366784 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29366784/
RECORD: Rec_0087517 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 29366784 PMID29366784 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29366784/
RECORD: Rec_0217898 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
310.6 μM
IC50
PaperPubMed PMID: 29366784 PMID29366784 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29366784/
RECORD: Rec_0220507 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
512 μM
MIC
PMID29366784 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29366784/
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