Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length384 amino acids

Chemical FormulaC1901H3009N519O548S11

DescriptionStandard

        ANPGFMVRITQAGLDYAHQQGIVILEKELAQMKLPDISGDSRIRHVGKVRYEISSLDLQSFTLPYSRISLAPNVGLQVSISNAFAEVDGDWRVKLFFIRDHGSFNLNVENVYLKIDLKLGSDDSGKPTVDTSSCSVRISRVRVRFSGRLGWLYNLFYNVVESRFRNILENKVCETVASSVRNDLQPYLRTLPVTARIDAKAGIDYSLVTPPTATAQSLDVGLKGEFFSMAQRSAVPFTPLPLALPPDHDRMVYFGASSFFFNTAGFAYHTAGALVFDITDAMVVSSRNGGLCRYPNLLPATLQLEKMYPDMPMKVRLSSSSAPSLNIRPGGLSLQPVVDVQAYAILPDSRLAPLFLLSLTGNVSAVIDVKSGHIVGKLNVGRYR
    

Molecular Weight42255.09 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)7.31

Net Charge (pH 7.4) 6.70

Charge Density (pH 7.0) 0.0190

GRAVY Index0.04

Hydrophobic Moment 0.60

Boman Index0.08

Instability Index40.86

Aliphatic Index 98.46

Aromaticity 0.0911

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0191472 VERIFIED: NO

Provenance & Taxonomy

OrganismPiaya cayana [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria