Peptide Database

Peptide NameH5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC107H181N31O25

DescriptionStandard

        YEIKINRHFKTLKKNLKK
    

Molecular Weight2301.77 Da

Isoelectric Point (pI)10.39

Net Charge (pH 7.0)5.84

Net Charge (pH 7.4) 5.58

Charge Density (pH 7.0) 0.3246

GRAVY Index-1.34

Hydrophobic Moment 0.75

Boman Index-0.44

Instability Index-6.32

Aliphatic Index 86.67

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 968.66

LogP -5.99

H-bond Donors 34.0

H-bond Acceptors 32.0

Rotatable Bonds 85.0

Heavy Atoms 163.0

Ring Count 3.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204154 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive

TargetCandida albicans ATCC 5314

Activity64 μg/mL

MethodMIC

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