Peptide Database

Peptide NameAndroctonus defensin

Function Ontology

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Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC172H251N55O48S7

DescriptionStandard

        GFGCPFDERACHAHCQSVGRRGGYCGNFRMTCYCYK
    

Molecular Weight4081.63 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.48

Charge Density (pH 7.0) 0.0799

GRAVY Index-0.52

Hydrophobic Moment 0.50

Boman Index-0.11

Instability Index57.79

Aliphatic Index 13.61

Aromaticity 0.1667

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1665.94

LogP -19.77

H-bond Donors 66.0

H-bond Acceptors 60.0

Rotatable Bonds 128.0

Heavy Atoms 282.0

Ring Count 9.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0095525 VERIFIED: YES

Provenance & Taxonomy

OrganismHaemaphysalis longicornis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)