Peptide Database

Peptide NamePenicillin-binding protein 1A (EC 3.4.16.4)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1848 amino acids

Chemical FormulaC8876H13692N2324O2922S57

DescriptionStandard

        MAENDNNKNNFTGKIKGKTKGKIKAKMAAWFTKTFIIFVMKVLPIFLLVCMVHTAFSWISDLVESVKNPADIYEIMGIDNISDLICVAGNADDGYYLAYKQGIDEKLDEVVKRYNKGSRQYVKKDVIKKMLDAELYTQYPNLGGKIGKEADVKIGESSNAASGGSDFSGTLYWPTDSTYVSSFFGLRNSPTAGASTNHGGIDISAVTGANVYACLDGTVTIAEHSDSAGNYVAIDHGNGYVTKYMHNSQLKVSVGDKVTAGQVIALAGSTGISTGPHVHFQVEKDGEKVDPLTFKYNNGKGASSSSSDSSSTTSTGTTTSSANKVTSLDGFLFIGDSITDGMKSEANVVDSTCTVRAVVGVGSKYWLDHYSEISSVSDVKGINIMLGTNDYDYGISYMKQLLEKLHGTFSNVTIYVDNLLPDKDSNTSEFKSYVSQLKEFCTSNSSYIKFIDPTSGVEIGSDGTHPTINGYKTLWNNIKSAILNGGGSSSSSVAPLIIAKDTGEGQDGFQGAIRIRRVTPNKTIGALTNVGTGATQTTTVVTGGLGTKEDIPESVKKQMEGISMQHFSGVDYSDLSYLTIPYFDFNGSVQQGHMVVNKKLADEVLLIFQELYKIKYPIEKMELIDNFSGSKKLTGDALDYASIEANNTSAFNDRKVVTNDGVQNTVSKHALGQAIDINPQINPYINPDGSFSHDNAKKYVKERKSQEGWSDTEKAACITPDSEIYKIFTKYGWTWLGNSSYTGDTQHFEKADLTNVKTIENREDVAGTSSSTTDTTDSNNTKKDGDNSNTNNSNNSSASSSNTSKQSEVEEYLKSAASGTWSVYAKDLTSNSDIASVNADAKMQSASVIKLFIMATAYDEMAKGNMVPTEVSSDIKLMITQSENFATNRMIDRLGFDKINNYIRSNGYTNTELNRYMLKSNANGDNYTSSKDAAKILENIYNHKCVSYEASEQMMAYLKAQQLRSKIPDGVPSGVQTANKTGELDTVENDAAIVFKDNAPYVLVVMSSGLSDTAKARQNIVDISKIVYGDGASVGGNSATVGSVTTAINSKIYDLKYIPESDFDKLVSDNDTKALEYFTLDGEWKLITAKWSYSSDDGVTISKNSPINYRSTVDKYTTPFEYLMDYYIDVKNRDFMFDFTDLVLKSELILAVEDNVTTTQTTTQSSISYADGTSEGGTSEVKLTEFVSDTMELTYVDTWFVKFTKESSYSAASFNSTQGALTGTQGQLIGNYKTTAYCYVCNDDGNGNFGTSVTASGAQATPNRTVAIHANGDPYGLKLGDQIMIEGDPTVYVVEDTGTGQPGAWRDIYIEAPTDENGQKYCACNSSPVGDRNVNVYWAQDVKAATESNSTDDDNSKALINTVASVKGTVTENISVSTNSSSGPSKMVLDKNTHGYYYVSSTKIDTITTHSIAIKYDTGESEIKGNENKFIKLFKDNKEAKSDLKPKWLITTVEKGEKTASFTDLTKYLLYKLTGESFGVTEFDFSIYEPGSFSSMSRGGGYDQFIRWFHAWEGMSGSLSADGTKYIIGDDGYGNITVGYGVDIFNGGFAERFAAAGYPTSVGSEVDKEFVDNLEKEEINEALQIVESKCGGLNLTQYQKYALVSRIYNCGDSGAFSNRNGKDFVSAFTSYWNQDKDLEYKVPANDGMFSHPLYTNYMCLPNTAKVGNSSVYSPGVDARRKAEWLLFKTGYYDRIDEFYEDGGNIVNAAAIVHDFISSNGYHYSLGDDLPGTVNDVKNARAVCCATFVSWTLYEAGYDWMVDCTGINSCATLLPFLEAHGGTKIMNPTMDMLQPGDILFYGSGGSSHTDIYIGDGLWYNCGSNDTVQRKDPYSKAIRADVYCVIRFDS
    

Molecular Weight201537.18 Da

Isoelectric Point (pI)4.92

Net Charge (pH 7.0)-60.35

Net Charge (pH 7.4) -62.71

Charge Density (pH 7.0) -0.0327

GRAVY Index-0.40

Hydrophobic Moment 0.69

Boman Index0.02

Instability Index24.35

Aliphatic Index 71.75

Aromaticity 0.1012

Extinction Coeff. Reduced 268510.00

Extinction Coeff. Oxidized 269760.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0366403 VERIFIED: YES

Provenance & Taxonomy

OrganismClostridium sp. 27_14 [Bacterium]

Tax ID1896979

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Non-hemolytic