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MYP_087126
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Basic Information
MAC1/10
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
13 amino acids
C72H129N17O14S
Standard
Sequence
GFKMALKLLKKVL
Physicochemical Analysis
1488.96 Da
10.48
3.76
3.55
0.2889
0.76
0.73
0.17
6.12
150.00
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
516.60
0.22
18.0
19.0
55.0
104.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095018 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
200 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. Peptides. 2012 Jan;33(1):18-26. doi: 10.1016/j.peptides.2011.11.002. PMID: 22100226. PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0133398 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human colon adenocarcinoma SW480
13
IC50
PMID24616110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24616110/
RECORD: Rec_0138945 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Macropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
SW
MTT/MTS assay
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0144458 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
CCRF-CEM
14±4 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. Peptides. 2012 Jan;33(1):18-26. doi: 10.1016/j.peptides.2011.11.002. PMID: 22100226. PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0145367 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
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