Peptide Database

Peptide NameDipeptidyl peptidase IV-inhibitory peptide 4

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC35H57N13O11

DescriptionStandard

        GPAGPQGPR
    

Molecular Weight835.91 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0845

GRAVY Index-1.36

Hydrophobic Moment 0.44

Boman Index-0.11

Instability Index43.31

Aliphatic Index 11.11

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 374.74

LogP -5.76

H-bond Donors 11.0

H-bond Acceptors 12.0

Rotatable Bonds 21.0

Heavy Atoms 59.0

Ring Count 3.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0003269 VERIFIED: YES

Provenance & Taxonomy

OrganismHypophthalmichthys molitrix [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory DPP-IV Inhibitory

TargetDipeptidyl peptidase IV

Activity842.10 ± 3.37 μM

MethodIC50

RECORD: Rec_0357792 VERIFIED: YES