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MYP_087094
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Basic Information
Mastoparan-C [K4,11,12R]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C72H134N24O16
Standard
Sequence
LNLRALLAVARRIL
Physicochemical Analysis
1591.99 Da
12.00
2.76
2.56
0.1971
1.15
0.78
0.09
77.71
209.29
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
670.41
-3.64
25.0
19.0
54.0
112.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0149695 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae ATCC 700603
16 μM
MIC
PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0157423 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis ATCC 23857
4 μM
MIC
PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0160744 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive bacteria: Staphylococcus aureus ATCC 25923
4 μM
MIC
PaperNewly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0210047 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Mouse erythrocytes
32 μM
Hemolysis
PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0232460 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 23857
4 μM
MIC
PaperNewly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
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