Peptide Database

Peptide NameCherimolacyclopeptide C

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC35H50N8O8

DescriptionStandard

        PGAAWIP
    

Molecular Weight710.82 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0059

GRAVY Index0.51

Hydrophobic Moment 0.18

Boman Index0.59

Instability Index-7.67

Aliphatic Index 84.29

Aromaticity 0.1429

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 230.93

LogP -0.32

H-bond Donors 8.0

H-bond Acceptors 8.0

Rotatable Bonds 16.0

Heavy Atoms 51.0

Ring Count 4.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0376064 VERIFIED: YES

Provenance & Taxonomy

OrganismAnnona cherimola [Plant]

FamilyCyclic Peptide

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytotoxic Anticancer

TargetKB (human nasophryngeal carcinoma) cells

Activity0.072 μM

MethodIC50