Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length272 amino acids

Chemical FormulaC1421H2143N335O407S13

DescriptionStandard

        MSSLGSEYVLGCHRLFFPTLWNTCHFPSGADLVLMHIKFILWLYNIEYFALFTIYTVPVRVDDLAEIDYSLNSLEVFRPYIDMDLKGIVHPAGNYTGPPYVATPFAIPDQSDSMLYLAFSEYFFQTSLFSYYTAGAFNITIAKETCRYLNISTEMFGSIIPEIAKYSIILYPVMMKLMATEIPLISLQQDSFTLEIQESMEVFAVLPDSTTQSLFTVNVAANTSIALNVFDQKLTGSLCLNRLQFSLAHSNVGSFEVSRQFKHIGNTNQDYQ
    

Molecular Weight30848.06 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-11.99

Net Charge (pH 7.4) -12.63

Charge Density (pH 7.0) -0.0441

GRAVY Index0.24

Hydrophobic Moment 0.72

Boman Index0.22

Instability Index48.50

Aliphatic Index 96.43

Aromaticity 0.1434

Extinction Coeff. Reduced 34840.00

Extinction Coeff. Oxidized 35090.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0119268 VERIFIED: NO

Provenance & Taxonomy

OrganismChrysolophus pictus (Golden pheasant) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria