Peptide Database

Peptide NameiAβ5p-C3

Function Ontology

beta-sheet breaker peptides

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC20H34N6O10S

DescriptionStandard

        NMESA
    

Molecular Weight550.58 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.2474

GRAVY Index-0.82

Hydrophobic Moment 0.29

Boman Index-0.09

Instability Index46.52

Aliphatic Index 20.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 280.34

LogP -4.16

H-bond Donors 9.0

H-bond Acceptors 10.0

Rotatable Bonds 18.0

Heavy Atoms 37.0

Ring Count 0.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0261561 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAmyloid-beta

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-Term(NMe)Sar

C-TermAmidation

Bio-Activity Profile

Function

beta-sheet breaker peptides

MethodRP-HPLC

Half-LifeHuman plasma, in vitro; 21600 s