‹ ›
MYP_087058
← PREVIOUS NEXT → BACK
Basic Information
D4D20-S4
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C131H224N34O35
Standard
Sequence
ALWDTLLKKVLKAAAKAALDAVLVGANA
Physicochemical Analysis
2835.39 Da
9.53
1.79
1.60
0.0641
0.84
0.71
0.28
-2.43
146.79
0.0357
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1106.81
-7.01
38.0
37.0
95.0
200.0
2.0
28.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0023284 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum HB3
1 μM
Percent inhibition; [3H] Hypoxanthine incorporation assay
PaperAntimalarial activities of dermaseptin S4 derivatives PMID10952593 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10952593/
RECORD: Rec_0023480 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum HB3
<10 μM
Percent inhibition; [3H] Hypoxanthine incorporation assay
PaperAntimalarial activities of dermaseptin S4 derivatives PMID10952593 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10952593/
RECORD: Rec_0025917 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
Vero cells:CC50=17
PMID23161023 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23161023/
RECORD: Rec_0067726 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli
PMID10660589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10660589/
RECORD: Rec_0106506 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HSV-2 acyclovir-resistant strain(ROI2):inhibition of cytopathic effet(CPE) of HSV-2 in Vero cells
9.63 μM
EC50
PMID23161023 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23161023/
1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 1 of 4