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MYP_087016
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Basic Information
Cicadin (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
55 amino acids
C283H427N89O95
Standard
Sequence
NEYHGFVDKANNENKRKKQQGRDDFVVKPNNFANRRRKDDYNENYYDDVDAADVV
Physicochemical Analysis
6595.96 Da
5.70
-1.14
-1.42
-0.0208
-1.75
0.54
-0.48
41.04
38.91
0.1273
5960.00
5960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3122.74
-36.78
104.0
95.0
225.0
467.0
9.0
65.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0071446 VERIFIED: YES
Provenance & Taxonomy
Cicada flammata [Animal]
186872
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV-1
HIV-1
1 μM
% inhibition
Mammalian: 1.4 h; Yeast: 3 min; E. coli: >10 h
PaperIsolation of cicadin, a novel and potent antifungal peptide from dried juvenile cicadas. | Wang H, Ng TB. | Peptides. 2002 Jan;23(1):7-11. | DOI:10.1016/s0196-9781(01)00573-3 | PMID:11814612 PMID11814612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11814612/
RECORD: Rec_0076688 VERIFIED: YES
Provenance & Taxonomy
Cicada flammata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Coprinus comatus
PMID11814612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11814612/
RECORD: Rec_0077675 VERIFIED: YES
Provenance & Taxonomy
Cicada flammata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
HIV-1 reverse transcriptase
PMID11814612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11814612/
RECORD: Rec_0092422 VERIFIED: YES
Provenance & Taxonomy
Cicada flammata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Mycosphaerella arachidicola
0.07 μM
MIC
PMID11814612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11814612/
RECORD: Rec_0096468 VERIFIED: YES
Provenance & Taxonomy
Cicada flammata [Animal]
186872
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV-1
HIV-1
0.1 μM
% inhibition
Mammalian: 1.4 h; Yeast: 3 min; E. coli: >10 h
PaperIsolation of cicadin, a novel and potent antifungal peptide from dried juvenile cicadas. | Wang H, Ng TB. | Peptides. 2002 Jan;23(1):7-11. | DOI:10.1016/s0196-9781(01)00573-3 | PMID:11814612 PMID11814612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11814612/
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