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MYP_087015
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Basic Information
Pancreastatin
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
48 amino acids
C212H333N61O82S
Standard
Sequence
SEALAVDGAGKPGAEEAQDPEGKGEQEHSQQKEEEEEMAVVPQGLFRG
Physicochemical Analysis
5080.34 Da
4.20
-9.42
-9.70
-0.1963
-1.16
0.42
-0.15
63.59
46.88
0.0208
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2314.10
-28.31
73.0
75.0
176.0
356.0
5.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070465 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Pancreastatin
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
29:Phosphoserine
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperThe spectrum of endogenous human chromogranin A-derived peptides identified using a modified proteomic strategy PMID12442257 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12442257/
RECORD: Rec_0130199 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Chromogranin/secretogranin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Ser29 Phosphoserine
Bio-Activity Profile
Secretory granule peptide Neuropeptide precursor
Evidence URLhttps://www.uniprot.org/uniprotkb/CMGA_HUMAN/entry
RECORD: Rec_0241754 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 43.8%, E 0.0%, T 31.2%, C 25.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0340454 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/