Peptide Database

Peptide NameSAR-endolysin (EC 3.2.1.17) (Endolysin) (Gene product 54) (gp54) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length178 amino acids

Chemical FormulaC854H1365N251O254S12

DescriptionStandard

        MANRAKLSAAVLSLILAGASAPQILDQFLDEKEGNSLTAYKDGSGIWTICRGATMVDGKPVMQGMKLTQAKCNQVNAIERNKALAWVDRNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRLNAGDRHGACEAIRWWIKDGGRDCRLTKGQKNGCYGQVERRDQESALTCWEIDQ
    

Molecular Weight19597.28 Da

Isoelectric Point (pI)9.04

Net Charge (pH 7.0)6.52

Net Charge (pH 7.4) 6.09

Charge Density (pH 7.0) 0.0367

GRAVY Index-0.42

Hydrophobic Moment 0.70

Boman Index-0.05

Instability Index37.48

Aliphatic Index 74.66

Aromaticity 0.0730

Extinction Coeff. Reduced 33460.00

Extinction Coeff. Oxidized 33960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8200.01

LogP -91.44

H-bond Donors 290.0

H-bond Acceptors 274.0

Rotatable Bonds 659.0

Heavy Atoms 1371.0

Ring Count 26.0

Amide Bonds 196.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238757 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage N15 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic