Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC699H1116N196O195S6

DescriptionStandard

        PKALPVAREPMLLMAVTEFVANSAAFTYFTAGALRRNISSDMLPQRFPLQLTTKSMGVFSPQLQERYGDQPMELHLWARRQPLLSCHPDALHGTLFSSAEAFVVLPNTTRVPVFLLNIDANVTGKPTITRNRLGGTVRLTG
    

Molecular Weight15577.92 Da

Isoelectric Point (pI)10.15

Net Charge (pH 7.0)5.22

Net Charge (pH 7.4) 4.98

Charge Density (pH 7.0) 0.0370

GRAVY Index-0.00

Hydrophobic Moment 0.45

Boman Index0.07

Instability Index55.72

Aliphatic Index 90.64

Aromaticity 0.0780

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6205.50

LogP -60.46

H-bond Donors 216.0

H-bond Acceptors 209.0

Rotatable Bonds 498.0

Heavy Atoms 1096.0

Ring Count 27.0

Amide Bonds 152.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0032921 VERIFIED: NO

Provenance & Taxonomy

OrganismMionectes macconnelli [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria