Peptide Database

Peptide NameXT-7 (CPF-ST3)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC83H149N21O21

DescriptionStandard

        GLLGPLLKIAAKVGSNLL
    

Molecular Weight1777.20 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0977

GRAVY Index1.12

Hydrophobic Moment 0.55

Boman Index0.43

Instability Index-9.42

Aliphatic Index 178.89

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 664.59

LogP -3.82

H-bond Donors 22.0

H-bond Acceptors 23.0

Rotatable Bonds 60.0

Heavy Atoms 125.0

Ring Count 1.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425425 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus tropicalis [Animal]

Tax ID8364

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anticancer

TargetS. saprophyticus

Activity13 μM

MethodMIC

RECORD: Rec_0425521 VERIFIED: YES

Provenance & Taxonomy

OrganismSilurana tropicalis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetL. acidophilus LA5 [

Activity250 μg/mL

MethodMBC

RECORD: Rec_0426158 VERIFIED: YES

Provenance & Taxonomy

OrganismSilurana tropicalis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa MDR1 B38084 [

Activity256 μg/mL

MethodMBC

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