‹ ›
MYP_086855
← PREVIOUS NEXT → BACK
Basic Information
Misgurin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C106H189N41O29
Standard
Sequence
RQRVEELSKFSKKGAAARRRK
Physicochemical Analysis
2501.89 Da
11.84
6.76
6.55
0.3220
-1.64
0.61
-0.75
80.69
46.67
0.0476
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1217.05
-14.46
46.0
36.0
93.0
176.0
1.0
21.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0325883 VERIFIED: YES
Provenance & Taxonomy
Oriental weatherfish [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Likely chlorinated. Synthetic peptide showed identical activity. Hence, chemical modification may be unimportant or does not occur (unless a modified aa is used)
Bio-Activity Profile
Antimicrobial Antifungal
S. mutans
16 μg/mL
MIC
PaperA novel antimicrobial peptide from the loach, Misgurnus anguillicaudatus.
RECORD: Rec_0327842 VERIFIED: NO
Provenance & Taxonomy
Misgurnus anguillicaduatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0331644 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Sheep erythrocytes
10 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/9271200/ PMID9271200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9271200/
RECORD: Rec_0337007 VERIFIED: YES
Provenance & Taxonomy
Oriental weatherfish [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Likely chlorinated. Synthetic peptide showed identical activity. Hence, chemical modification may be unimportant or does not occur (unless a modified aa is used)
Bio-Activity Profile
Antimicrobial Antifungal
S. typhimurium
8 μg/mL
MIC
PaperA novel antimicrobial peptide from the loach, Misgurnus anguillicaudatus.
RECORD: Rec_0340341 VERIFIED: YES
Provenance & Taxonomy
Misgurnus anguillicaudatus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
PMID9271200 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9271200/
FIRST PREV 1 ... 6 7 8 9 10 NEXT LAST
Showing 5 records on this page · Page 8 of 10