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MYP_086831
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Basic Information
PAF26
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
6 amino acids
C49H67N13O7
Standard
Sequence
RKKWFW
Physicochemical Analysis
950.14 Da
11.17
2.76
2.55
0.4597
-1.88
0.07
-0.45
8.33
0.00
0.5000
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
354.34
1.03
14.0
10.0
29.0
69.0
5.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0262417 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Screened from [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
N-terminal acetylation and C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal
in 20% Dixon, A. niger
20 μM
MIC
PaperIdentification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library.
RECORD: Rec_0272642 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
Escherichia coli DH5α
160 μM
MIC
PMID11976121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976121/
RECORD: Rec_0276326 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
A. niger CBS 120.49
8 μM
MIC
PMID11976121;28556271;28428776 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976121/
RECORD: Rec_0278444 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Screened from [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
N-terminal acetylation and C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal
Saccharomyces cerevisiae W303-1A
>160 μM
MIC
PaperIdentification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library.
RECORD: Rec_0287734 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Ac
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-negative
Fusarium oxysporum CECT2866
80 μM
MIC
PMID11976121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976121/
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