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MYP_086831
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Basic Information
PAF26
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
6 amino acids
C49H67N13O7
Standard
Sequence
RKKWFW
Physicochemical Analysis
950.14 Da
11.17
2.76
2.55
0.4597
-1.88
0.07
-0.45
8.33
0.00
0.5000
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
354.34
1.03
14.0
10.0
29.0
69.0
5.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0133308 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli DH5alpha
160 μM
IC50
PMID11976121;28556271;28428776 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976121/
RECORD: Rec_0138704 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Screened from [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
N-terminal acetylation and C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal
B. cinerea CECT2100
60 μM
MIC
PaperIdentification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library.
RECORD: Rec_0141601 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
C. glabrata
50 μM
MIC50
PMID11976121;28556271;28428776 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976121/
RECORD: Rec_0147950 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Ac
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-negative
Escherichia coli DH5
160
MIC
PMID11976121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976121/
RECORD: Rec_0154101 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Antifungal Hemolytic Anti-Gram-positive Anti-Gram-negative
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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