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MYP_086827
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Basic Information
Lividin 8 HLmb
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
20 amino acids
C107H180N30O24
Standard
Sequence
AVPLIYKRPGVYVTKRPKGK
Physicochemical Analysis
2270.76 Da
10.66
5.79
5.59
0.2895
-0.54
0.48
-0.15
54.48
87.50
0.1000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
878.42
-5.21
31.0
30.0
72.0
161.0
5.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002973 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0141268 VERIFIED: YES
Provenance & Taxonomy
Hydrophylax bahuvistara [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus MTCC 9542
200 μM
MIC
PMID26960362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26960362/
RECORD: Rec_0173428 VERIFIED: YES
Provenance & Taxonomy
Hydrophylax bahuvistara [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus coagulans ATCC 7050
200 μM
MIC
PMID26960362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26960362/
RECORD: Rec_0276742 VERIFIED: YES
Provenance & Taxonomy
Hydrophylax bahuvistara [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
200 μM
MIC
PMID26960362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26960362/
RECORD: Rec_0387744 VERIFIED: YES
Provenance & Taxonomy
Hydrophylax bahuvistara [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
Hemolysis
PMID26960362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26960362/