Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC307H515N77O86S2

DescriptionStandard

        MFLELISKLNLSSNIAEKIVAVLDAGSDVATVVAMFTTFGVGALAIQTGKQILKKQGKKAAVKF
    

Molecular Weight6724.97 Da

Isoelectric Point (pI)9.78

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.27

Charge Density (pH 7.0) 0.0547

GRAVY Index0.61

Hydrophobic Moment 0.63

Boman Index0.24

Instability Index19.65

Aliphatic Index 118.91

Aromaticity 0.0625

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2631.27

LogP -22.35

H-bond Donors 90.0

H-bond Acceptors 92.0

Rotatable Bonds 235.0

Heavy Atoms 472.0

Ring Count 4.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0278533 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus sp. BF2-3 [Bacterium]

FamilyBacteriocin

Tax ID2217827

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal