Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC348H550N100O100S5

DescriptionStandard

        MRQRFCKLPNRDSKNLERERPKLPKFDDFDLNVKQASEKDVVKPEVGSRYLCTPGSCWKWVCFTTTA
    

Molecular Weight7895.03 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)4.47

Net Charge (pH 7.4) 4.17

Charge Density (pH 7.0) 0.0667

GRAVY Index-0.87

Hydrophobic Moment 0.68

Boman Index-0.26

Instability Index42.61

Aliphatic Index 53.73

Aromaticity 0.1045

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3284.33

LogP -32.33

H-bond Donors 118.0

H-bond Acceptors 110.0

Rotatable Bonds 262.0

Heavy Atoms 553.0

Ring Count 14.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0223994 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus sp [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria