Peptide Database

Peptide NameBrevinin-2Ta

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC354H587N93O114S6

DescriptionStandard

        MFTMKKSLLLFFFLGTISLSLCQEERNADEDDGEMTEEEKRGILDTLKNLAKTAGKGILKSLVNTASCKLSGQC
    

Molecular Weight8162.39 Da

Isoelectric Point (pI)5.33

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0204

GRAVY Index-0.17

Hydrophobic Moment 0.71

Boman Index-0.01

Instability Index28.48

Aliphatic Index 88.38

Aromaticity 0.0541

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3388.09

LogP -35.07

H-bond Donors 120.0

H-bond Acceptors 119.0

Rotatable Bonds 291.0

Heavy Atoms 567.0

Ring Count 4.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375148 VERIFIED: NO

Provenance & Taxonomy

OrganismRana temporaria [Animal]

FamilyFrog skin active peptide (FSAP)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence