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MYP_086679
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Basic Information
Peptide YY (PYY) (Peptide tyrosine tyrosine)
Antimicrobial
Antimicrobial ▸ Antifungal
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Neuropeptide Y family
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
36 amino acids
C190H287N53O58
Standard
Sequence
YPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY
Physicochemical Analysis
4241.63 Da
6.77
-0.15
-0.42
-0.0041
-1.09
0.67
-0.22
92.99
62.50
0.1389
7450.00
7450.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1803.71
-16.74
63.0
59.0
131.0
301.0
10.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0261380 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0290817 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
NPY family
9823; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
13-Ser: Phosphoserine
Bio-Activity Profile
Hormone NPY-family Neuropeptide signaling
PaperPDB 1RU5 structural record; NMR; chain A; residues 1-36
RECORD: Rec_0333175 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperPeptide YY: A Paneth cell antimicrobial peptide that maintains Candida gut commensalism
RECORD: Rec_0347916 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
NPY
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Ser13 Phosphoserine
Bio-Activity Profile
NPY-family Neuropeptide Neuromodulator
PMID3413293 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3413293/
RECORD: Rec_0406481 VERIFIED: YES
Provenance & Taxonomy
Jaculus jaculus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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