Peptide Database

Peptide NameSomatostatin-37

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitory neuropeptide

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Inhibitory neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC180H286N54O48S2

DescriptionStandard

        ALRAAAVAGSPQQLLPLGQRERKAGCKNFFWKTFSSC
    

Molecular Weight4038.66 Da

Isoelectric Point (pI)10.32

Net Charge (pH 7.0)4.78

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.1291

GRAVY Index-0.20

Hydrophobic Moment 0.48

Boman Index-0.03

Instability Index55.72

Aliphatic Index 66.22

Aromaticity 0.1081

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1663.47

LogP -17.90

H-bond Donors 60.0

H-bond Acceptors 55.0

Rotatable Bonds 132.0

Heavy Atoms 284.0

Ring Count 7.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0037761 VERIFIED: NO

Provenance & Taxonomy

OrganismPetromyzon marinus [Animal]

FamilySomatostatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0113071 VERIFIED: YES

Provenance & Taxonomy

OrganismPetromyzon marinus [Animal]

FamilySomatostatin

Tax ID7757

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide26-37

Bio-Activity Profile

Function

Hormone Inhibitory neuropeptide

RECORD: Rec_0345465 VERIFIED: YES

Provenance & Taxonomy

OrganismPetromyzon marinus [Animal]

FamilySomatostatin

Tax ID7757

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide26-37

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0358216 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/