Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC981H1561N269O264S9

DescriptionStandard

        PTPPPVAHEPMLLLAVTEFVANSAAFTYFTAGALRRNISSDMLPRRFPLQLRTKSMEVFSPQLQERYPDQPMELQLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELARTPLPALCRAQVLPVPQVKHLETLLKFGLWLFGVPRANSKCCPCPVP
    

Molecular Weight21636.12 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)6.28

Net Charge (pH 7.4) 5.92

Charge Density (pH 7.0) 0.0320

GRAVY Index0.03

Hydrophobic Moment 0.57

Boman Index0.09

Instability Index58.19

Aliphatic Index 95.05

Aromaticity 0.0714

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8335.96

LogP -102.71

H-bond Donors 285.0

H-bond Acceptors 283.0

Rotatable Bonds 673.0

Heavy Atoms 1523.0

Ring Count 45.0

Amide Bonds 211.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283146 VERIFIED: NO

Provenance & Taxonomy

OrganismChloropsis hardwickii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria