Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC258H415N71O84S4

DescriptionStandard

        MNAKTNKEINYEAVATLQEVKIDDLDILLGGAGHGVNTISAECRWNSLQAIFTCC
    

Molecular Weight5983.74 Da

Isoelectric Point (pI)4.70

Net Charge (pH 7.0)-3.43

Net Charge (pH 7.4) -3.76

Charge Density (pH 7.0) -0.0624

GRAVY Index0.01

Hydrophobic Moment 0.42

Boman Index0.10

Instability Index48.23

Aliphatic Index 97.64

Aromaticity 0.0545

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2523.49

LogP -26.98

H-bond Donors 88.0

H-bond Acceptors 86.0

Rotatable Bonds 202.0

Heavy Atoms 417.0

Ring Count 5.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152348 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus suis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria