Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC924H1459N251O250S9

DescriptionStandard

        PTELATEHEPMLLLAITEFVANSAAFTYFTAGALHRNISSDMLPQRFPLQLKTKSMGLFSPKLQERYPNHPMELHLSARRQPLLSCRPDALHGTLFSSAEAFVVLPNATRVPVFLLNIDANVTGKPIITRNRLGGTVSLKGPACPAPGSAVCPVPQVKRLENLLKFALWLFGVPWANSECCPHPVP
    

Molecular Weight20372.59 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)5.45

Net Charge (pH 7.4) 4.99

Charge Density (pH 7.0) 0.0293

GRAVY Index0.06

Hydrophobic Moment 0.62

Boman Index0.12

Instability Index56.62

Aliphatic Index 93.39

Aromaticity 0.0753

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7818.44

LogP -89.43

H-bond Donors 268.0

H-bond Acceptors 270.0

Rotatable Bonds 639.0

Heavy Atoms 1434.0

Ring Count 43.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189663 VERIFIED: NO

Provenance & Taxonomy

OrganismGlareola pratincola (Collared pratincole) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria