Peptide Database

Peptide NameDermaseptin-PC percursor

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC384H618N100O120S3

DescriptionStandard

        MAFLKKSLFLVLFFGLVSFSICEEEKRENKDEIEQEEDDKSEEKRALWKSILKNVGKAAGKAVLNAVTDMVNQGEQ
    

Molecular Weight8651.81 Da

Isoelectric Point (pI)4.97

Net Charge (pH 7.0)-3.48

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.0458

GRAVY Index-0.42

Hydrophobic Moment 0.68

Boman Index-0.07

Instability Index57.18

Aliphatic Index 87.24

Aromaticity 0.0789

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3628.12

LogP -31.91

H-bond Donors 123.0

H-bond Acceptors 120.0

Rotatable Bonds 310.0

Heavy Atoms 607.0

Ring Count 7.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380952 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa coelestis [Bacterium]

FamilyFrog skin active peptide (FSAP) family; Dermaseptin subfamily

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Amphibian defense peptide Non-hemolytic Non-ribosomal