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MYP_086583
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hemostasis ▸ Antithrombotic activity
Metabolic ▸ Lipid metabolism ▸ Cholesterol-lowering
Standard
7 amino acids
C36H65N9O8S
Standard
Sequence
MAIPPKK
Physicochemical Analysis
784.02 Da
10.00
1.50
1.28
0.2141
-0.40
0.19
-0.02
49.60
70.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
272.38
-0.60
8.0
11.0
24.0
54.0
2.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020781 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
kappa-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
IC50
PaperVascular effects and antihypertensive properties of kappa-casein macropeptide | Miguel, M. et al. | DOI: 10.1016/j.idairyj.2007.04.009 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0085447 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]
ACE-inhibitory peptide
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperBioactive Peptides of Buffalo, Camel, Goat, Sheep, Mare, and Yak Milks and Milk Products
RECORD: Rec_0117533 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
kappa-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antithrombotic Hypocholesterolemic
PaperBioactive peptides released by in vitro digestion of standard and hydrolyzed infant formulas | Wada, Y. et al. | DOI: 10.1016/j.peptides.2015.09.005 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0118581 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antithrombotic
PaperJolles P., L¨¦vy-Toledano S., Fiat A.-M., Soria C., Gillessen O., Thomaidis A., Dunn F. W., Caen J. P.. Analogy between fibrinogen and casein. Effect of an undecapeptide isolated from ?-casein on platelet function. Eur. J. Biochem., 158, 379-382.
RECORD: Rec_0119263 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
28 mmHg
SBP decrease
PaperAntihypertensive peptides from food proteins: a review. PMID22249830 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22249830/
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