Peptide Database

Peptide NameAngiotensin I-converting enzyme-inhibitory peptide 2

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC30H48N6O8

DescriptionStandard

        TLKYP
    

Molecular Weight620.74 Da

Isoelectric Point (pI)8.26

Net Charge (pH 7.0)0.40

Net Charge (pH 7.4) 0.20

Charge Density (pH 7.0) 0.0792

GRAVY Index-0.74

Hydrophobic Moment 0.40

Boman Index-0.02

Instability Index15.70

Aliphatic Index 78.00

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 237.41

LogP -0.65

H-bond Donors 8.0

H-bond Acceptors 9.0

Rotatable Bonds 17.0

Heavy Atoms 44.0

Ring Count 2.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211234 VERIFIED: YES

Provenance & Taxonomy

OrganismRaja clavata [Animal]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-converting enzyme

Activity170.00 μM

MethodIC50

RECORD: Rec_0270015 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

Activity170.0

MethodIC50