Peptide Database

Peptide NameRHS repeat-associated core domain containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length2518 amino acids

Chemical FormulaC12751H19771N3401O4076S55

DescriptionStandard

        MVLTYKGLKIETPYDAVQVEDINIIEHINDHAALELKLLIEEGKIFECINKNVSEEKVTVIRIDEDTNEEMKLFVGKINSVTMFYEGELHIMKIQCISYTKDFDIKKNSRTFCNLDMTYQEVIQMVLKPYSNKAFTDNLTNGQTIGGFILQYEETEWEFLKRIASHFNGVLLSECTEEYGRFHFGIPKIDNQKEIELEDYEVVKDIDNFNKREALGIEDNYLQEYTTWDIVSSKKLKLGEQVTFNKVKCVVEKIHTEVYKEEIRTIYTLGIQRGLRSTYKVNHNIFGMSIPATVKDVKGNTMSVHFEIDPEYEVYENQKYFTYAIESSAWYCMPEKESKVHIYFPTNDEKDAIAVHAVRAQGSEAKYAGRTQNPDNKSFSNTTGSEMKLTPSDMSFAADDSRTVCLTLAQSGNVSLVGQNINFTASENLQLGMREAEGDSPPLRPQNIQLSAKSKIEVAKGSIGVQMVDETFLKAATIKYEGTIKDPAELPDEIAHRNDGDAEQIEKINDQAKAMEEQKIDAAKQKMGFGAIALAIGVAAVVVAATVFTGGLALAAIGVGVTAALVGGSELAEGSSNYTKARSGDYSKSYNFMRDTVCGGNETLYNIVKYGSVLISSVVVAIGTGGTATEVLLKMGSDAGGDVAINLIADYADDGKIDGNLSDYIESAIMSASMSNVNIGVMNKFKKLEEAEKLSCKTLGKIRLASDVALDMGSQLATTGDANFTGTFIKKYIGNKLCFSDPVDGATGSLYIPATDMVLPDITEEFKIERKYESVNSRVGLLGRGWTASFETCLEFHEEKINVLCSDGHIETFDRINDEWINDKGGAKIYSLVNKEGYWIFKVSTEKKVYRYNKLGKLIDITDKNNNKLSVTYIRENIETITTFSNYKLFFTYKDEKVIEIKDDLDRTVQYKYAGNYLTDVIHVDKGITRYTYDEKGYISSITDQNGNTYTKNFFDKRGRVIRQDFPNDDSCKITYDDSEKEVTFYYTKSQRTEKTRFNKDGLITHLFYEDGTTEEYKYDAYQNKVYIKDRNGFETHKVYDEFGNLLKEAMPNGLITEYTYDEKGNLIKETDNEGKEIIYDYDSSDNLKSTKTKISVGNWKTESYTYDSYGRILSKTDGNKNTLKYEYENISDLEGKKGKDPVRVITSSNYIYEYTYDKVGRNTEIKTDYGVIEFAYNHLNFVAKIKDANGNITIKNYDNMGNLISLYTPNACSDGSISEEGYRYTYDHMDRLISIKNPLGIVEKSIRDSEGNIIKGINPNYYSDETYDGIGVEYVYDKDNRKIKTIYPDGGIERFFYDANGNVIKHISPEYYQEETDDGLGYSYTYDSMNRLNSIINEEGIVEKTFEYDLHGNIIKEIDNEGNATLFKYDLLGNLIEKRVPVEKDFYGNIKYNLTCYIYDKNSNKTLEKHGTGAVSEKGICNNYHEIYFEYDEGNRLVEVKDKYGAKARYKYDCLNNKTFESFKINDGTTKAIHYIYDKVGNLIQKKEEINGIFVSLEAKGKNVWAITNYEYDKNGNITKIVTPKGFEIGRVYDKTDRLIEQHEKDETNGIFRSYVYKYDKANNITSISEYSGEEAKLISSKYISENDYRVHWSERYEKKKENERLFGRLDFREDKKQKTYVYDAQNRLTHFINFLGNTTRLFYDKNDRIIKQVLPEQYDEGADDGVGTTYTYNVKGQVVEVKNALGETITKNTYDPKGNLKTRVDGENNKVEYTYTLLGQIKEVITPNSRKENKAAQSYKYDVRGNITGITDGNGNETSYVLDDWGRIIQITTPEGGVEKYTYDYAGNITSTTDANGGTIEYIYNSLGQVCEIKDQEGNSEYFYYDNEGNLTKHIDRNKNHVDRSYNLDRNIVSVKAYQVDEEAIALEAKKAEEDRIKAIEEARIKAVEAAKKRIEEGSVFTPLSQGHRRRSFTEREKEKKEKQERGLEQSTSKIEIAEDPNKNKLQVISQRFNYNPDGTLRSAYTWNMQYEYSYNIEGLLESKSASGRTLLRYTYDKNNNIKTIKDITGKSSIYNYDETNRVKLIQDDNENTLATYDYYKNDNIKSVSLGNGLKTDYTYDGDGNVQSLVTITSNGEVLVDYNYAYDLNGNRLQKVSSKHKNFYTYDSMNRLKEASYDDRCESFTYDKVGNRLTKTTNDITEKYVYNIKNQIREMHNKNGINYFTYDNQGNTIKEGTSTGNNIFEYNTLNQQVKAITKEGNTLISRYDAEGLRVEIEENEKLTKFIFHKDNVLVETDKDYNVISRFARGYEVVAADIADSEVDSKLNRYFYTVDEQGSTTCITDANQQIRNEYWYDAFGNVLEGREQVHNRITYTGQQYDSVTGQYYLRARFYNPVIGRFTQEDVYRGDGLNLYAYCGNNPVRYYDPSGYQLAACAPKKRQINAEELRNSPGITTQNNKIDVNQNKLMYQSGNIGVIPQEIKDRLNNRTFNNFKELRSALWEEVGNSKYATEFGKSGQTLMKNGMAPYSNSGKYVIHHKQPIAKGGGVYDLDNLIILSPKMHKIIIDSKYHFGKKG
    

Molecular Weight287690.30 Da

Isoelectric Point (pI)5.35

Net Charge (pH 7.0)-59.11

Net Charge (pH 7.4) -62.62

Charge Density (pH 7.0) -0.0235

GRAVY Index-0.71

Hydrophobic Moment 0.81

Boman Index-0.09

Instability Index36.85

Aliphatic Index 75.02

Aromaticity 0.1100

Extinction Coeff. Reduced 344170.00

Extinction Coeff. Oxidized 345545.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0261022 VERIFIED: NO

Provenance & Taxonomy

OrganismClostridium sp. Maddingley MBC34-26 [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

MethodQualitative functional evidence