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MYP_086506
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
24 amino acids
C118H196N32O32
Standard
Sequence
GFKDWIKGAAKKLIKTVASSIANQ
Physicochemical Analysis
2575.01 Da
10.18
3.76
3.55
0.1565
-0.10
0.65
0.05
-9.48
93.75
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1062.68
-9.68
37.0
36.0
90.0
182.0
3.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0066059 VERIFIED: YES
Provenance & Taxonomy
Ascaphus truei [Animal]
Ascaphin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
25.0 μM
MIC
PaperJ.M. Conlon et al. / Biochemical and Biophysical Research Communications 320 (2004) 170-175. The ascaphins: a family of antimicrobial peptides from the skin secretions of the most primitive extant frog, Ascaphus truei
RECORD: Rec_0094054 VERIFIED: YES
Provenance & Taxonomy
Ascaphus truei [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
25 μM
MIC
PMID15207717 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15207717/
RECORD: Rec_0145647 VERIFIED: YES
Provenance & Taxonomy
Ascaphus truei [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
25 μM
MIC
PaperThe ascaphins: a family of antimicrobial peptides from the skin secretions of the most primitive extant frog, Ascaphus truei.
RECORD: Rec_0182594 VERIFIED: YES
Provenance & Taxonomy
Ascaphus truei [Animal]
Ascaphin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
3.0 μM
MIC
PaperJ.M. Conlon et al. / Biochemical and Biophysical Research Communications 320 (2004) 170-175. The ascaphins: a family of antimicrobial peptides from the skin secretions of the most primitive extant frog, Ascaphus truei
RECORD: Rec_0231465 VERIFIED: YES
Provenance & Taxonomy
Ascaphus truei [Animal]
Ascaphin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
200
HC50
PMID15207717 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15207717/
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