Peptide Database

Peptide NameDEFA3 isoform 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC449H720N126O127S8

DescriptionStandard

        MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIPADNPEVVVSLAWDKSLAPKHPGSRKNMACYCRIPACLAGETRYGTCIYQGRLWAFCC
    

Molecular Weight10171.81 Da

Isoelectric Point (pI)7.57

Net Charge (pH 7.0)0.54

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0057

GRAVY Index0.19

Hydrophobic Moment 0.44

Boman Index0.11

Instability Index44.45

Aliphatic Index 96.81

Aromaticity 0.0638

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3999.91

LogP -35.62

H-bond Donors 142.0

H-bond Acceptors 137.0

Rotatable Bonds 323.0

Heavy Atoms 710.0

Ring Count 16.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283929 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Antibiotic Defensin Non-hemolytic Non-ribosomal