Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length721 amino acids

Chemical FormulaC3384H5279N919O1058S16

DescriptionStandard

        MSTVLYIHPPHGCYVFKMEINMSDNETVPTQGVDYGHTIVGWPVRPKWGQPDAGASIGINPDFDPVTGNGWLPEEDGYNHDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDPTVAWDPVFVYFPAKAVSDSDLSAGSLPETVPVHSRIQDDVHDGAQFISVTGSGSQPYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSELHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVVLPEGPLKQRQEEENQARAKADAEAEAKAKAEAEAKAKEKAEREALFARAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEVLSSLGAAVGRAIASLGATATAGTAGPMVAAASAILFPPAAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPPPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPVYVMLSGPYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFGELPDNKVMIDRLENILNGGLQATDTDLRFYTHEIRELERYRNLGVKDGVIPDNYDEVWNNTHTATLEDYKINEKTQPLYTPEAEEAYRKAEEGK
    

Molecular Weight76277.68 Da

Isoelectric Point (pI)4.88

Net Charge (pH 7.0)-31.09

Net Charge (pH 7.4) -32.28

Charge Density (pH 7.0) -0.0431

GRAVY Index-0.28

Hydrophobic Moment 0.77

Boman Index0.07

Instability Index33.72

Aliphatic Index 78.13

Aromaticity 0.0666

Extinction Coeff. Reduced 78270.00

Extinction Coeff. Oxidized 78395.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213669 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica subsp. enterica serovar Give [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)