Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length300 amino acids

Chemical FormulaC1510H2344N366O442S10

DescriptionStandard

        IKINAFSLPNTSLAFVPGVGIRALINHGTANISTDWEIKSPLFQDTGGADLFLSGVYFTGIVVLAWNDFGHPILKLQNCCAQVSHSDVSFSGELSVLYNSFSEPMEKPILKNLNKMLCPIITSEVEALNANLSMLKALRKIDNYTLLDYSLISSPEITENYVDLNLKGVFYPLENLTDTPFSSVPFVLPEHSDSMIYIGISENFFKSASYAYFTAGAFNVTLTTKEIFNHLIRNSQGLGSMLSRIAELYILSQPFMVKVLATEPPVVNLLPGNFTLDVPASFVIFTQSKNSTAKTIVSMD
    

Molecular Weight33017.60 Da

Isoelectric Point (pI)5.12

Net Charge (pH 7.0)-7.80

Net Charge (pH 7.4) -8.37

Charge Density (pH 7.0) -0.0260

GRAVY Index0.24

Hydrophobic Moment 0.69

Boman Index0.21

Instability Index32.65

Aliphatic Index 103.00

Aromaticity 0.1067

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26025.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101863 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera physalus (Fin whale) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria