Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Beta-1;4-N-acetylmuramidase) (Lysozyme) (Lytic enzyme) (Muramidase) (Protein P15)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length149 amino acids

Chemical FormulaC773H1183N213O222S8

DescriptionStandard

        MQYTLWDIISRVESNGNLKALRFEPEYYQRRMERGDWDNSIIQNIRAANKCSLGTARMIYCSSWGAVQIMGFNLYLNGAFNLSVAHFMENEAYQVNEFRRFLLKNGLTEYTPERLASDKAARVKFAKVYNGAESYADLILQACQFYGVK
    

Molecular Weight17268.48 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)2.57

Net Charge (pH 7.4) 2.22

Charge Density (pH 7.0) 0.0173

GRAVY Index-0.34

Hydrophobic Moment 0.58

Boman Index-0.02

Instability Index28.77

Aliphatic Index 78.66

Aromaticity 0.1409

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31525.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7135.13

LogP -65.54

H-bond Donors 252.0

H-bond Acceptors 234.0

Rotatable Bonds 576.0

Heavy Atoms 1216.0

Ring Count 27.0

Amide Bonds 167.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204583 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacteria phage PRD1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Anti-Gram-negative Glycosidase Hydrolase Cytolytic Non-hemolytic

TargetGram Negative Bacteria