Peptide Database

Peptide NameGE-25

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC123H189N37O41

DescriptionStandard

        GWRPNSREDSVEAGLPLQVRGYPEE
    

Molecular Weight2842.04 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-2.22

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.0889

GRAVY Index-1.20

Hydrophobic Moment 0.31

Boman Index-0.23

Instability Index81.22

Aliphatic Index 58.40

Aromaticity 0.0800

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1270.21

LogP -13.61

H-bond Donors 43.0

H-bond Acceptors 39.0

Rotatable Bonds 89.0

Heavy Atoms 201.0

Ring Count 6.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0110670 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyGE

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods6:Phosphoserine; 10:Phosphoserine

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Receptor modulation Immunomodulatory

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour