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MYP_086422
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Basic Information
Aurein-5.2 (Frogs, amphibians, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
25 amino acids
C110H194N28O32S
Standard
Sequence
GLMSSIGKALGGLIVDVLKPKTPAS
Physicochemical Analysis
2452.95 Da
9.70
1.76
1.55
0.0703
0.60
0.47
0.29
28.30
124.80
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
940.42
-8.83
32.0
35.0
82.0
171.0
2.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0331592 VERIFIED: YES
Provenance & Taxonomy
Ranoidea raniformis [Animal]
116057
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
P.multocida
>100 μg/mL
MIC
PaperThe antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.
RECORD: Rec_0342866 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea [Animal]
Aurein
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S.uberis.
PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
RECORD: Rec_0343979 VERIFIED: YES
Provenance & Taxonomy
Ranoidea raniformis [Animal]
116057
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Micrococcus luteus
>100 μg/mL
MIC
PaperThe antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.
RECORD: Rec_0360696 VERIFIED: YES
Provenance & Taxonomy
Litoria raniformis [Animal]
Aurein
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anticancer
Streptococcus uberis
50 μg/mL
MIC
PaperHost-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance. Peptides. 2004 Jun;25(6):1035-1054. doi: 10.1016/j.peptides.2004.03.006. PMID: 15203252. PMID10951191;15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
RECORD: Rec_0363277 VERIFIED: YES
Provenance & Taxonomy
Ranoidea raniformis [Animal]
116057
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus aureus
>100 μg/mL
MIC
PaperThe antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.
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