Peptide Database

Peptide NameAlpha-defensin 22 (Defensin-related cryptdin-22)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC449H736N138O141S7

DescriptionStandard

        MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR
    

Molecular Weight10547.94 Da

Isoelectric Point (pI)7.58

Net Charge (pH 7.0)0.55

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0059

GRAVY Index-0.52

Hydrophobic Moment 0.70

Boman Index-0.18

Instability Index61.58

Aliphatic Index 79.68

Aromaticity 0.0538

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4581.38

LogP -51.20

H-bond Donors 166.0

H-bond Acceptors 150.0

Rotatable Bonds 361.0

Heavy Atoms 735.0

Ring Count 9.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337242 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic