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MYP_086416
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Basic Information
Protonectin [L2,8F]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C64H103N13O14
Standard
Sequence
IFGTILGFLKGL
Physicochemical Analysis
1278.58 Da
8.75
0.76
0.55
0.0633
1.68
0.39
0.68
3.99
162.50
0.1667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
429.67
-0.15
15.0
15.0
42.0
91.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017051 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
256 μg/mL
MIC
PMID33244888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33244888/
RECORD: Rec_0022473 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
128 μg/mL
MIC
PMID33244888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33244888/
RECORD: Rec_0032491 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
>64 μM
HC50
PMID33244888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33244888/
RECORD: Rec_0049735 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Cryptococcus neoformans ATCC 208821
32 μg/mL
MIC
PMID33244888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33244888/
RECORD: Rec_0055835 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human colon adenocarcinoma HCT 116 50-60% Killing
9.8
PMID33244888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33244888/
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