Peptide Database

Peptide NameFresolimumab

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length447 amino acids

Chemical FormulaC2168H3377N569O678S17

DescriptionStandard

        QVQLVQSGAEVKKPGSSVKVSCKASGYTFSSNVISWVRQAPGQGLEWMGGVIPIVDIANYAQRFKGRVTITADESTSTTYMELSSLRSEDTAVYYCASTLGLVLDAMDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPSCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK
    

Molecular Weight48805.52 Da

Isoelectric Point (pI)6.73

Net Charge (pH 7.0)-0.70

Net Charge (pH 7.4) -1.54

Charge Density (pH 7.0) -0.0016

GRAVY Index-0.31

Hydrophobic Moment 0.66

Boman Index0.03

Instability Index45.91

Aliphatic Index 72.91

Aromaticity 0.0895

Extinction Coeff. Reduced 70820.00

Extinction Coeff. Oxidized 71445.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0051051 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

FamilyImmunoglobulin

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immunomodulatory

RECORD: Rec_0416481 VERIFIED: NO