Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC337H495N81O84S8

DescriptionStandard

        MKFQHFMFLALLVFLSITYGENAAVELPWGCSNYNGVCRPICQAAELPFGPFGCAKGFVCCVAHVY
    

Molecular Weight7281.55 Da

Isoelectric Point (pI)6.68

Net Charge (pH 7.0)-0.38

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0058

GRAVY Index0.69

Hydrophobic Moment 0.61

Boman Index0.35

Instability Index10.15

Aliphatic Index 84.24

Aromaticity 0.1667

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2555.48

LogP -15.91

H-bond Donors 91.0

H-bond Acceptors 94.0

Rotatable Bonds 223.0

Heavy Atoms 510.0

Ring Count 18.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0311320 VERIFIED: NO

Provenance & Taxonomy

OrganismClupea harengus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence