Peptide Database

Peptide NameSLAY-screened peptide P3694

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC75H107N21O23S2

DescriptionStandard

        MHLNCNDFTPVHGSY
    

Molecular Weight1734.91 Da

Isoelectric Point (pI)5.93

Net Charge (pH 7.0)-1.34

Net Charge (pH 7.4) -1.67

Charge Density (pH 7.0) -0.0890

GRAVY Index-0.43

Hydrophobic Moment 0.21

Boman Index0.11

Instability Index46.50

Aliphatic Index 45.33

Aromaticity 0.1333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 703.46

LogP -7.57

H-bond Donors 24.0

H-bond Acceptors 26.0

Rotatable Bonds 51.0

Heavy Atoms 121.0

Ring Count 5.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0263817 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/